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Peptide record

TPDB05620

Antibacterial Anticancer Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB05620
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFFFRRRR
Physicochemical Analysis
C60H86N20O9
ANDCEQGHILKMPSTWYV
RF
1231.47
12.88
4
0
4
+4
-1.28
-0.850
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
4
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C60H86N20O9
1231.47
12.88
+4
-1.28
-0.850
Evidence Records 2 records
Evidence 1 Activity

Activity

15% Killing
Toxicity
100 µM
Cytotoxic
15% Killing | 100 | µM | target cell: Pig kidney epithelial cells PK1

Target

Pig kidney epithelial cells PK1

Source & Reference

NA
DBAASP
Design, Synthesis, and Evaluation of Amphiphilic Cyclic and Linear Peptides Composed of Hydrophobic and Positively-Charged Amino Acids as Antibacterial Agents. | Molecules | 2018
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Molecules. 2018 Oct 22 23(10):2722.