Back to search

Peptide record

TPDB05577

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05577
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
WWWLKKIW
Physicochemical Analysis
C68H88N14O9
ARNDCEQGHMFPSTYV
W
1245.54
10.60
2
0
6
+2
-6.29
-0.388
97.50
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1766.31
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
8
C68H88N14O9
1245.54
10.60
+2
-6.29
-0.388
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5-25 µM

Target

Escherichia coli K12

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MI
Evidence 2 Activity

Activity

MIC
Antibacterial
6.2 µM

Target

Staphylococcus epidermidis 1457

Source & Reference

dbAMP

Other

Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also ac
Evidence 3 Activity

Activity

MIC
Antibacterial
6.2 µM

Target

B. subtilis 168

Source & Reference

dbAMP

Other

Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
6.2 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
6.2-12.5 µM

Target

C. glabrata

Source & Reference

dbAMP

Other

aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
1.6 µM

Target

C. tropicalis

Source & Reference

dbAMP

Other

>25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
12.5-25 µM

Target

Escherichia coli K12

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MI
Evidence 8 Activity

Activity

MIC
Antifungal
6.2 µM

Target

Staphylococcus epidermidis 1457

Source & Reference

dbAMP CAFPdb

Other

Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also ac
Evidence 9 Activity

Activity

MIC
Antifungal
6.2 µM

Target

B. subtilis 168

Source & Reference

dbAMP CAFPdb

Other

Active against E. coli K12 (MIC 12.5-25 uM), S. epidermidis 1457 (MIC 6.2 uM), B. subtilis 168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC
Evidence 10 Activity

Activity

MIC
Antifungal
6.2 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb

Other

168 (MIC 6.2 uM), and S. aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 11 Activity

Activity

MIC
Antifungal
6.2-12.5 µM

Target

C. glabrata

Source & Reference

dbAMP CAFPdb

Other

aureus USA300 (MIC 3.1-6.2 uM MBC >25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 12 Activity

Activity

MIC
Antifungal
1.6 µM

Target

C. tropicalis

Source & Reference

dbAMP CAFPdb

Other

>25 uM). Also active against C. albicans (MIC 6.2 uM), C. glabrata (MIC 6.2-12.5 uM), and C. tropicalis (MIC 1.6 uM).
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
50% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and surface immobilization of short anti-biofilm peptides. | Acta Biomater | 2017
Evidence 14 Activity

Activity

50% Hemolysis
Toxicity
55 µM
Hemolytic Cytotoxic
50% Hemolysis | 55 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Design and surface immobilization of short anti-biofilm peptides. | Acta Biomater | 2017
Evidence 15 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Chicken erythrocytes

Target

Chicken erythrocytes

Source & Reference

NA
DBAASP
Design and surface immobilization of short anti-biofilm peptides. | Acta Biomater | 2017
Evidence 16 Activity

Activity

50% Cell death
Toxicity
50 µM
Cytotoxic
50% Cell death | 50 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Design and surface immobilization of short anti-biofilm peptides. | Acta Biomater | 2017
Evidence 17 Activity

Activity

50% Cell death
Toxicity
50 µM
Cytotoxic
50% Cell death | 50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design and surface immobilization of short anti-biofilm peptides. | Acta Biomater | 2017
Evidence 18 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis