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Peptide record

TPDB05532

Antibacterial Hemolysis Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB05532
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
SKHWLWLW
Physicochemical Analysis
C60H78N14O10
ARNDCEQGIMFPTYV
W
1155.37
10.10
2
0
5
+1
-4.59
-0.375
97.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
16500
1428.12
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
2
L
1
K
0
M
0
F
0
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 2 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
8
C60H78N14O10
1155.37
10.10
+1
-4.59
-0.375
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
20 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 20 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antibacterial agents based on the cyclic D,L-alpha-peptide architecture. | Nature | 2001
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis