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Peptide record

TPDB05522

Antibacterial Antiviral Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB05522
Antibacterial Antiviral Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antiviral, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
GLPVCGETCVGGTCNTPGCTCSWPVCTRK
Physicochemical Analysis
C119H193N35O39S6
ADQHIMFY
C
2930.41
7.63
2
1
5
+1
2.83
0.138
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
200.48
13
Residue Composition
number
0
A
1
R
1
N
0
D
6
C
1
E
0
Q
5
G
0
H
0
I
1
L
1
K
0
M
0
F
3
P
1
S
5
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 1 T: 5 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C119H193N35O39S6
2930.41
7.63
+1
2.83
0.138
Evidence Records 2 records
Evidence 1 Activity

Activity

55% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
55% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. | J Biol Chem | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis