Back to search

Peptide record

TPDB05495

Antibacterial Antiviral Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05495
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP AVPpred-BWR dbAMP 3.0 DRAVP 2.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
ATCYCRTGRCATRESLSGVCEIRGRLYRLCCR
Physicochemical Analysis
C147H251N53O44S6
NDQHKMFPW
R
3657.30
8.90
7
2
9
+5
4.84
-0.228
64.06
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
3355
91.73
13
Residue Composition
number
2
A
7
R
0
N
0
D
6
C
2
E
0
Q
3
G
0
H
1
I
3
L
0
K
0
M
0
F
0
P
2
S
3
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 0 C: 6 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 0 M: 0 F: 0 P: 0 S: 2 T: 3 W: 0 Y: 2 V: 1
Chemical Descriptors
32
C147H251N53O44S6
3657.30
8.90
+5
4.84
-0.228
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human cervical epithelial cells CaSki

Target

Human cervical epithelial cells CaSki

Source & Reference

NA
DBAASP
Enhancement of antiviral activity of human alpha-defensin 5 against herpes simplex virus 2 by arginine mutagenesis at adaptive evolution sites. | J Virol | 2013
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.23269800]No cytotoxicity against CaSki cells up to 100µg/ ml.

Source & Reference

NA
DRAMP
J Virol. 2013 Mar 87(5):2835-45.