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Peptide record

TPDB05478

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB05478
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGPAFHSVSNFAKKHKTA
Physicochemical Analysis
C94H139N27O24
RDCEQILMWY
AKF
2031.30
10.84
5
0
7
+3
2.35
-0.437
31.05
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
2
H
0
I
0
L
3
K
0
M
3
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 0 K: 3 M: 0 F: 3 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C94H139N27O24
2031.30
10.84
+3
2.35
-0.437
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug
Evidence 2 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant stra
Evidence 4 Activity

Activity

MIC
Antibacterial
3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

oli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MI
Evidence 5 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP

Other

yphimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

E. faecium

Source & Reference

dbAMP DRAMP

Other

(MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC ~36 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug
Evidence 8 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP Antifungipept

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug
Evidence 9 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP Antifungipept

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant stra
Evidence 10 Activity

Activity

MIC
Antifungal
3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

oli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MI
Evidence 11 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP DRAMP Antifungipept

Other

yphimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC
Evidence 12 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

E. faecium

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC ~36 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiparasitic
1-2 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug
Evidence 14 Activity

Activity

MIC
Antiparasitic
1-2 µg/mL

Target

S. typhimurium

Source & Reference

DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug
Evidence 15 Activity

Activity

MIC
Antiparasitic
1-2 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant stra
Evidence 16 Activity

Activity

MIC
Antiparasitic
3 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

oli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MI
Evidence 17 Activity

Activity

MIC
Antiparasitic
1 µg/mL

Target

L. monocytogenes

Source & Reference

DRAMP

Other

yphimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC
Evidence 18 Activity

Activity

MIC
Antiparasitic
1 µg/mL

Target

E. faecium

Source & Reference

DRAMP

Other

(MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC ~36 ug/ml).
Evidence 19 Activity

Activity

MIC
Antiviral
1-2 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug
Evidence 20 Activity

Activity

MIC
Antiviral
1-2 µg/mL

Target

S. typhimurium

Source & Reference

DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug
Evidence 21 Activity

Activity

MIC
Antiviral
1-2 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

killed E. coli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant stra
Evidence 22 Activity

Activity

MIC
Antiviral
3 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

oli (MIC 1-2 ug/ml), S. typhimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MI
Evidence 23 Activity

Activity

MIC
Antiviral
1 µg/mL

Target

L. monocytogenes

Source & Reference

DRAMP

Other

yphimurium (MIC 1-2 ug/ml), P. aeruginosa (MIC 1-2 ug/ml), Gram+ S. aureus (MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC
Evidence 24 Activity

Activity

MIC
Antiviral
1 µg/mL

Target

E. faecium

Source & Reference

DRAMP

Other

(MIC 3 ug/ml), L. monocytogenes (MIC 1 ug/ml), vancomycin-resistant strain (anti-VRE) of E. faecium (MIC 1 ug/ml), and C. albicans (MIC ~36 ug/ml).