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Peptide record

TPDB05465

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB05465
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLSVLGSVVKHVIPHVVPVIAEHL
Physicochemical Analysis
C123H206N32O30
RNDCQMFTWY
V
2613.19
8.06
4
1
14
+0
4.53
1.312
178.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
3
H
2
I
4
L
1
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 3 I: 2 L: 4 K: 1 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 7
Chemical Descriptors
25
C123H206N32O30
2613.19
8.06
+0
4.53
1.312
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
12.5 µM
Cytotoxic
50% Cell death | 12.5 | µM | target cell: Human endocervical cells End1/E6E7

Target

Human endocervical cells End1/E6E7

Source & Reference

NA
DBAASP
Inhibition of HIV Infection by Caerin 1 Antimicrobial Peptides | Peptides | 2015
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.26026377]Human endocervical cells End1/E6E7:50% cell death at 12.5 µM.

Source & Reference

NA
DRAMP
Peptides. 2015 Sep 71:296-303. ##Peptides. 2004 Jun 25(6):1035-1054.##J. Chem. Res. 1993 138: 910-936.