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Peptide record

TPDB05456

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB05456
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept APD_complete APD_hemolytic ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDSLKNLAKNAGQILLNKASCKLSGQC
Physicochemical Analysis
C128H226N38O40S2
REHMFPTWYV
L
3001.55
9.72
4
1
11
+3
3.06
0.069
117.93
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.16
10
Residue Composition
number
3
A
0
R
3
N
1
D
2
C
0
E
2
Q
3
G
0
H
2
I
6
L
4
K
0
M
0
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 3 D: 1 C: 2 E: 0 Q: 2 G: 3 H: 0 I: 2 L: 6 K: 4 M: 0 F: 0 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
29
C128H226N38O40S2
3001.55
9.72
+3
3.06
0.069
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
Hemolysis
100 µM
[Ref.8163497]LC50>100 µM against human erythrocytes

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J Biol Chem. 1994 Apr 22 269(16):11956-11961.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

LC50
Toxicity
100 µM
Hemolytic
Hemolytic_activity: [Ref.8163497]LC50>100 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
Evidence 3 Hemolysis

Activity

100 µM
LC50
[Ref.8163497]LC50>100 µM against human erythrocytes
Hemolysis

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
DRAMP4
APD_complete APD_hemolytic