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Peptide record

TPDB05451

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB05451
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb AVPpred-BWR
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC
Physicochemical Analysis
C169H295N45O48S3
RDHPSWY
K
3821.65
9.98
6
2
16
+4
5.49
0.376
105.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.27
8
Residue Composition
number
5
A
0
R
1
N
0
D
2
C
2
E
1
Q
5
G
0
H
4
I
4
L
6
K
1
M
1
F
0
P
0
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 2 E: 2 Q: 1 G: 5 H: 0 I: 4 L: 4 K: 6 M: 1 F: 1 P: 0 S: 0 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C169H295N45O48S3
3821.65
9.98
+4
5.49
0.376
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
4.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (20
Evidence 3 Activity

Activity

MIC
Antibacterial
8.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (2012) J Prot, http://dx.doi.org/10.1016/j
Evidence 4 Activity

Activity

MIC
Antifungal
8.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
4.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (20
Evidence 6 Activity

Activity

MIC
Antifungal
8.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (2012) J Prot, http://dx.doi.org/10.1016/j
Evidence 7 Activity

Activity

MIC
Antiparasitic
8.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
4.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (20
Evidence 9 Activity

Activity

MIC
Antiparasitic
8.5 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (2012) J Prot, http://dx.doi.org/10.1016/j
Evidence 10 Activity

Activity

MIC
Antiviral
8.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
4.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 8.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (20
Evidence 12 Activity

Activity

MIC
Antiviral
8.5 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 4.3 ug/ml), Gram+ bacteria S. aureus (MIC 4.3 ug/ml), and yeast C. albicans (MIC 8.5 ug/ml). Found in multiple species. See also Liu et al (2012) J Prot, http://dx.doi.org/10.1016/j