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Peptide record

TPDB05438

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB05438
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 Antifungipept APD_complete APD_hemolytic ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDTLKNLAISAAKGAAQGLVNKASCKLSGQC
Physicochemical Analysis
C138H243N41O44S2
REHMFPWY
A
3244.82
9.72
4
1
14
+3
2.91
0.309
109.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.85
10
Residue Composition
number
6
A
0
R
2
N
1
D
2
C
0
E
2
Q
4
G
0
H
2
I
5
L
4
K
0
M
0
F
0
P
3
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 2 G: 4 H: 0 I: 2 L: 5 K: 4 M: 0 F: 0 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C138H243N41O44S2
3244.82
9.72
+3
2.91
0.309
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
Hemolysis
100 µM
[Ref.8163497]LC50>100 µM against human erythrocytes

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J Biol Chem. 1994 Apr 22 269(16):11956-11961.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

LC50
Toxicity
100 µM
Hemolytic
Hemolytic_activity: [Ref.8163497]LC50>100 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
Evidence 3 Hemolysis

Activity

100 µM
LC50
[Ref.8163497]LC50>100 µM against human erythrocytes
Hemolysis

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
DRAMP4
APD_complete APD_hemolytic