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Peptide record

TPDB05431

LDP Antibacterial Antifungal Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB05431
LDP
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CAFPdb dbAMP CPPsite3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KWRRKLKKLR
Physicochemical Analysis
C65H118N24O11
ANDCEQGHIMFPSTYV
K
1411.81
12.72
7
0
3
+7
3.42
-2.240
78.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
389.57
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C65H118N24O11
1411.81
12.72
+7
3.42
-2.240
Free
L
Linear
Free
N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against MRSA, B. subtilis, E. coli, S. typhimurium, X. oryzae, and M. smegmatis demonstrated in vitro.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against MRSA, B. subtilis, E. coli, S. typhimurium, X. oryzae, and M. smegmatis demonstrated in vitro.
Evidence 3 Activity

Activity

Cell-penetrating Peptides

Target

Mrsa And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC-labelled at N-terminus
LDP showed that 98% of MRSA exhibited simultaneous FITC and PI staining
In vitro
CCSSHHHHHHHHHHHHHHHCC
Additional Detail Fields 1 fields
CCSSHHHHHHHHHHHHHHHCC