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Peptide record

TPDB05410

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB05410
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 dbACP iACP-DRLF AFP-GFuse Antifp Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
FFSMIPKIATGIASLVKNL
Physicochemical Analysis
C97H160N22O24S1
RDCEQHWY
I
2050.53
10.60
2
0
11
+2
-1.55
1.095
128.42
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
2
K
1
M
2
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 2 M: 1 F: 2 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C97H160N22O24S1
2050.53
10.60
+2
-1.55
1.095
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
100 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
25 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 12.5 uM), and C. albicans (MIC 25 uM).
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 16 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 8 Activity

Activity

5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 32 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 9 Activity

Activity

25% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 10 Activity

Activity

65% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
65% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 11 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.