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Peptide record

TPDB05387

Antibacterial Anticancer Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB05387
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLPVCGETCVGGTCNSPGCTCSWPVCTRN
Physicochemical Analysis
C116H185N35O40S6
ADQHIKMFY
C
2902.32
5.90
1
1
5
-0
2.25
0.148
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
202.42
14
Residue Composition
number
0
A
1
R
2
N
0
D
6
C
1
E
0
Q
5
G
0
H
0
I
1
L
0
K
0
M
0
F
3
P
2
S
4
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 3 S: 2 T: 4 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C116H185N35O40S6
2902.32
5.90
-0
2.25
0.148
Evidence Records 2 records
Evidence 1 Activity

Activity

12.3% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
12.3% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting | Chembiochem | 2014
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: Weak active up to 50 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Chembiochem. 2014 Sep 5 15(13):1956-65.