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Peptide record

TPDB05384

Antibacterial Anticancer Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB05384
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RLLSLIRKLIT
Physicochemical Analysis
C61H116N18O14
ANDCEQGHMFPWYV
L
1325.70
12.41
3
0
6
+3
0.02
0.891
212.73
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C61H116N18O14
1325.70
12.41
+3
0.02
0.891
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
25.0 µM
Hemolytic Cytotoxic
0% Hemolysis | 25.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Natural and redesigned wasp venom peptides with selective antitumoral activity. | Beilstein J Org Chem | 2018
Evidence 2 Activity

Activity

50% Cell death
Toxicity
100 µM
Cytotoxic
50% Cell death | 100 | µM | target cell: Normal breast cells MCF-10a

Target

Normal breast cells MCF-10a

Source & Reference

NA
DBAASP
Natural and redesigned wasp venom peptides with selective antitumoral activity. | Beilstein J Org Chem | 2018
Evidence 3 Activity

Activity

MHC
Toxicity
25.00 µm
Hemolytic Cytotoxic
Hemolytic_activity: Human red blood cells: MHC=25.00 µmol/L | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Beilstein J Org Chem. 2018 Jul 6 14:1693-1703.