Back to search

Peptide record

TPDB05370

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05370
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIKDWIKGAAKKLIKTVASHIANQ
Physicochemical Analysis
C118H200N34O31
RCEMFPY
K
2591.10
10.71
6
1
11
+4
4.17
-0.133
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
212.27
4
Residue Composition
number
4
A
0
R
1
N
1
D
0
C
0
E
1
Q
2
G
1
H
4
I
1
L
5
K
0
M
0
F
0
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 4 L: 1 K: 5 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C118H200N34O31
2591.10
10.71
+4
4.17
-0.133
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The ascaphins: a family of antimicrobial peptides from the skin secretions of the most primitive extant frog, Ascaphus truei. | Biochem Biophys Res Commun | 2004
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis