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Peptide record

TPDB05366

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB05366
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
MDFIIDIIKKIVGLFTGK
Physicochemical Analysis
C98H163N21O24S1
ARNCEQHPSWY
I
2051.56
9.76
3
2
10
+1
1.06
0.989
146.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
2
D
0
C
0
E
0
Q
2
G
0
H
5
I
1
L
3
K
1
M
2
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 5 L: 1 K: 3 M: 1 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C98H163N21O24S1
2051.56
9.76
+1
1.06
0.989
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
4790±90 µM
Hemolytic Cytotoxic
50% Hemolysis | 4790±90 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
8760±2080 µM
Hemolytic Cytotoxic
50% Hemolysis | 8760±2080 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
2000±120 µM
Hemolytic Cytotoxic
50% Hemolysis | 2000±120 | µM | target cell: Guinea pig erythrocytes

Target

Guinea pig erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
5350±600 µM
Hemolytic Cytotoxic
50% Hemolysis | 5350±600 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
6340±3540 µM
Hemolytic Cytotoxic
50% Hemolysis | 6340±3540 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis