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Peptide record

TPDB05358

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB05358
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 41-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
DYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR
Physicochemical Analysis
C214H324N68O55S6
EHIMV
RC
4921.71
9.60
9
2
10
+7
3.06
-1.080
23.90
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
19855
403.42
15
Residue Composition
number
2
A
6
R
2
N
2
D
6
C
0
E
1
Q
2
G
0
H
0
I
2
L
3
K
0
M
1
F
5
P
2
S
2
T
3
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 2 D: 2 C: 6 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 2 K: 3 M: 0 F: 1 P: 5 S: 2 T: 2 W: 3 Y: 2 V: 0
Chemical Descriptors
41
C214H324N68O55S6
4921.71
9.60
+7
3.06
-1.080
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
10% Hemolysis | 10 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins | J Biol Chem | 1999
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis