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Peptide record

TPDB05351

Antibacterial Antiviral Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB05351
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
GIIDIAKKLFESW
Physicochemical Analysis
C73H114N16O19
RNCQHMPTYV
I
1519.80
6.99
2
2
7
-0
0.73
0.385
127.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
361.89
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
3
I
1
L
2
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C73H114N16O19
1519.80
6.99
-0
0.73
0.385
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 20.1 uM).
Evidence 2 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 20.1 uM).
Evidence 3 Activity

Activity

50% Cell death
Toxicity
>65.8 µM
Cytotoxic
50% Cell death | >65.8 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.20086159]CEM-SS cells:TC50(cause 50% Cell death) >65.8 µM.

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2010 Mar 54(3):1343-6.