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Peptide record

TPDB05350

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB05350
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
INLKAIAALVKKVL
Physicochemical Analysis
C71H132N18O16
RDCEQGHMFPSTWY
ALK
1493.94
10.84
3
0
10
+3
0.72
1.357
202.14
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
14
C71H132N18O16
1493.94
10.84
+3
0.72
1.357
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

active against S. aureus (50% killing ED50 2 uM) and K+ effleux is demonstrated. In vitro Toxicity: 50% hemolysis (HC50) 50-100 uM. human RBC: HC50 197.7 uM rat RBC: HC50 253.4 uM. Less hemo.lytic ( Ye et al., 2023 ). Updated 7/2024
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

active against S. aureus (50% killing ED50 2 uM) and K+ effleux is demonstrated. In vitro Toxicity: 50% hemolysis (HC50) 50-100 uM. human RBC: HC50 197.7 uM rat RBC: HC50 253.4 uM. Less hemo.lytic ( Ye et al., 2023 ). Updated 7/2024
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

active against S. aureus (50% killing ED50 2 uM) and K+ effleux is demonstrated. In vitro Toxicity: 50% hemolysis (HC50) 50-100 uM. human RBC: HC50 197.7 uM rat RBC: HC50 253.4 uM. Less hemo.lytic ( Ye et al., 2023 ). Updated 7/2024