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Peptide record

TPDB05334

Antibacterial Antiviral Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB05334
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
GRFKRFRKKFKKLFK
Physicochemical Analysis
C98H160N30O16
ANDCEQHIMPSTWYV
K
2014.54
12.72
9
0
5
+9
3.30
-1.487
26.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
6
K
0
M
4
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 6 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C98H160N30O16
2014.54
12.72
+9
3.30
-1.487
Evidence Records 2 records
Evidence 1 Activity

Activity

50% cell death
Toxicity
>49.6 µM
Cytotoxic
50% cell death | >49.6 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins | Antimicrob Agents Chemother | 2008
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.18591279]CEM-SS cells:TC50>49.6 µM.(TC50:the concentration that reduced cell viability by 50%)

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2008 Sep 52(9):3438-40.