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Peptide record

TPDB05309

Antibacterial Anticancer Antifungal standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB05309
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 DRAMP Peptipedia CancerPPD 2.0 dbACP Antifungipept
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV
Physicochemical Analysis
C157H269N45O43S7
RNQHIFSY
K
3699.56
9.23
8
2
11
+6
6.42
-0.117
54.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
158.80
8
Residue Composition
number
5
A
0
R
0
N
1
D
6
C
1
E
0
Q
5
G
0
H
0
I
3
L
8
K
1
M
0
F
2
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 3 K: 8 M: 1 F: 0 P: 2 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
36
C157H269N45O43S7
3699.56
9.23
+6
6.42
-0.117
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.4 µM

Target

C. glutamicum

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Turgencin AMox1 (72% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A
Evidence 2 Activity

Activity

MIC
Antibacterial
0.4 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Turgencin AMox1 (72% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly
Evidence 3 Activity

Activity

MIC
Antibacterial
6.3 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly toxic to the human melan
Evidence 4 Activity

Activity

MIC
Antibacterial
0.8 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

ive against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly toxic to the human melanoma cancer cell line A
Evidence 5 Activity

Activity

MIC
Antifungal
0.4 µM

Target

C. glutamicum

Source & Reference

DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms.
Turgencin AMox1 (72% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A
Evidence 6 Activity

Activity

MIC
Antifungal
0.4 µM

Target

B. subtilis

Source & Reference

DRAMP Antifungipept

Other

Turgencin AMox1 (72% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly
Evidence 7 Activity

Activity

MIC
Antifungal
6.3 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP Antifungipept

Other

% Mox1, 28% Mox0) is active against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly toxic to the human melan
Evidence 8 Activity

Activity

MIC
Antifungal
0.8 µM

Target

Escherichia coli

Source & Reference

DRAMP Antifungipept

Other

ive against C. glutamicum (MIC 0.4 uM), B. subtilis (MIC 0.4 uM), S. aureus (MIC 6.3 uM), E. coli (MIC 0.8 uM), P. aeruginosa, A2058 (MIC 1.6 uM). Highly toxic to the human melanoma cancer cell line A