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Peptide record

TPDB05295

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB05295
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
AVAGEKLWLLPHLLKMLLTPTP
Physicochemical Analysis
C117H193N27O27S1
RNDCQIFSY
L
2442.04
9.88
3
1
12
+1
0.33
0.650
146.36
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
225.22
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
1
H
0
I
7
L
2
K
1
M
0
F
3
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 7 K: 2 M: 1 F: 0 P: 3 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
22
C117H193N27O27S1
2442.04
9.88
+1
0.33
0.650
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
60.8 µg/mL

Target

p. massiliense

Source & Reference

NA

Other

Active against M. abscessus subsp. massiliense (MIC 60.8 ug/ml). Also active against S. aureus.
Evidence 2 Activity

Activity

MIC
Antifungal
60.8 µg/mL

Target

p. massiliense

Source & Reference

Antifungipept

Other

Active against M. abscessus subsp. massiliense (MIC 60.8 ug/ml). Also active against S. aureus.
Evidence 3 Activity

Activity

2% Hemolysis
Toxicity
121.6 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 121.6 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimycobacterial Activity of a New Peptide Polydim-I Isolated from Neotropical Social Wasp Polybia dimorpha. | PLoS One | 2016