Peptide record

TPDB05288

Antibacterial Antiviral Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB05288
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AI4AVP, and other sources, with an available 3D structural model.
Sequence
ATCYCRTGRCATRESRSGVCEISGRLYRLCCR
Physicochemical Analysis
C144H245N53O45S6
NDQHKMFPW
R
3631.22
8.90
7
2
8
+5
5.53
-0.372
51.88
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
3355
92.39
14
Residue Composition
number
2
A
7
R
0
N
0
D
6
C
2
E
0
Q
3
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
3
S
3
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 0 C: 6 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 2 V: 1
Chemical Descriptors
32
C144H245N53O45S6
3631.22
8.90
+5
5.53
-0.372
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human cervical epithelial cells CaSki

Target

Human cervical epithelial cells CaSki

Source & Reference

NA
DBAASP
Enhancement of antiviral activity of human alpha-defensin 5 against herpes simplex virus 2 by arginine mutagenesis at adaptive evolution sites. | J Virol | 2013
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.23269800]No cytotoxicity against CaSki cells up to 100µg/ ml.

Source & Reference

NA
DRAMP
J Virol. 2013 Mar 87(5):2835-46.