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Peptide record

TPDB05268

Antibacterial Anticancer Antifungal Antiparasitic standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05268
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLFSLIKAGAKFLGKNLLKQGAQYAACKVSKEC
Physicochemical Analysis
C159H264N42O43S2
RDHMPTW
K
3516.22
10.12
6
1
15
+5
2.39
0.152
94.85
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1615
45.93
9
Residue Composition
number
5
A
0
R
1
N
0
D
2
C
1
E
2
Q
3
G
0
H
1
I
5
L
6
K
0
M
2
F
0
P
3
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 2 E: 1 Q: 2 G: 3 H: 0 I: 1 L: 5 K: 6 M: 0 F: 2 P: 0 S: 3 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
33
C159H264N42O43S2
3516.22
10.12
+5
2.39
0.152
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes
Evidence 2 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
1.56 µg/mL

Target

M. luteus ATCC934

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1
Evidence 4 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

dbAMP DRAMP

Other

6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9
Evidence 5 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

dbAMP DRAMP

Other

(MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025
Evidence 6 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

dbAMP DRAMP

Other

4 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025
Evidence 7 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes
Evidence 8 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC
Evidence 9 Activity

Activity

MIC
Antifungal
1.56 µg/mL

Target

M. luteus ATCC934

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

dbAMP DRAMP Antifungipept

Other

6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9
Evidence 11 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

dbAMP DRAMP Antifungipept

Other

(MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025
Evidence 12 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

dbAMP DRAMP Antifungipept

Other

4 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025
Evidence 13 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Staphylococcus aureus 209P

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes
Evidence 14 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC
Evidence 15 Activity

Activity

MIC
Antiparasitic
1.56 µg/mL

Target

M. luteus ATCC934

Source & Reference

DRAMP

Other

Active against S. aureus 209P (MIC 6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1
Evidence 16 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Streptococcus pyogenes COOK

Source & Reference

DRAMP

Other

6.25 ug/ml), B. subtilis ATCC 6633 (MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9
Evidence 17 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

Escherichia coli NIHJ

Source & Reference

DRAMP

Other

(MIC 6.25 ug/ml), M. luteus ATCC934 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025
Evidence 18 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

DRAMP

Other

4 (MIC 1.56 ug/ml), S. pyogenes COOK (MIC 12.5 ug/ml), E. coli NIHJ (MIC 12.5 ug/ml), and P. aeruginosa PAO1 (MIC 100 ug/ml). Updated 7/2019 9/2025