Back to search

Peptide record

TPDB05221

Seq ID No. 26 from patent ID US202000079827A1 Antibacterial Anticancer Antifungal Antiparasitic standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05221
Seq ID No. 26 from patent ID US202000079827A1
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
Sequence
RRWVRRVRRVWRRVVRVVRRWVRR
Physicochemical Analysis
C151H260N66O25
ANDCEQGHILKMFPSTY
R
3400.15
13.48
13
0
11
+13
5.54
-1.150
96.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
485.27
0
Residue Composition
number
0
A
13
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
8
V
Amino Acid Distribution
A: 0 R: 13 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 8
Chemical Descriptors
24
C151H260N66O25
3400.15
13.48
+13
5.54
-1.150
Free
L
Linear
Free
Antimicrobial and Anticancer
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell viability
Cell viability < 50% at 20 µM
Anticancer
<50 % at 20 µM

Target

Lung Cancer
H-460
Lung

Assay & Model

Tetrazolium-based assay
2-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
US20200079827A1

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Cell viability
Cell viability > 50% at 20 µM
Anticancer
>50 % at 20 µM

Target

Lung Cancer
Calu-1
Lung

Assay & Model

Tetrazolium-based assay
2-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
US20200079827A1