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Peptide record

TPDB05218

Antibacterial Anticancer Antifungal Antiparasitic standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB05218
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC
Physicochemical Analysis
C147H260N42O43S3
REQFPTWY
K
3400.12
9.98
7
2
13
+4
6.46
0.270
112.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.68
7
Residue Composition
number
2
A
0
R
1
N
2
D
2
C
0
E
0
Q
4
G
1
H
1
I
5
L
6
K
1
M
0
F
0
P
4
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 0 G: 4 H: 1 I: 1 L: 5 K: 6 M: 1 F: 0 P: 0 S: 4 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
33
C147H260N42O43S3
3400.12
9.98
+4
6.46
0.270
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
40 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevin
Evidence 2 Activity

Activity

MIC
Antibacterial
120 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevinin 2T (ref?). Found in multiple species. Updated 11/2012 GW
Evidence 3 Activity

Activity

MIC
Antifungal
40 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevin
Evidence 4 Activity

Activity

MIC
Antifungal
120 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevinin 2T (ref?). Found in multiple species. Updated 11/2012 GW
Evidence 5 Activity

Activity

MIC
Antiparasitic
40 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevin
Evidence 6 Activity

Activity

MIC
Antiparasitic
120 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

It is active against E. coli (MIC 40 uM) but only very weakly active against S. aureus (MIC 120 uM). It is also reported as brevinin 2T (ref?). Found in multiple species. Updated 11/2012 GW