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Peptide record

TPDB05213

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB05213
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
YPCKLNLKLGKVPFH
Physicochemical Analysis
C84H133N21O18S1
ARDEQIMSTW
LK
1757.17
10.07
4
0
6
+3
1.34
-0.160
97.33
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
84.80
3
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
1
G
1
H
0
I
3
L
3
K
0
M
1
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 3 K: 3 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C84H133N21O18S1
1757.17
10.07
+3
1.34
-0.160
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
1.3-80 µM
Hemolytic Cytotoxic
0% Hemolysis | 1.3-80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The antifungal activity of the peptide, periplanetasin-2, derived from American cockroach Periplaneta americana. | Biochem J | 2017
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016