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Peptide record

TPDB05209

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB05209
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GVVDILKGAAKDIAGHLASKVM
Physicochemical Analysis
C97H169N27O28S1
RNCEQFPTWY
A
2193.63
9.76
4
2
12
+1
4.11
0.655
128.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
0
R
0
N
2
D
0
C
0
E
0
Q
3
G
1
H
2
I
2
L
3
K
1
M
0
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 2 L: 2 K: 3 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C97H169N27O28S1
2193.63
9.76
+1
4.11
0.655
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
222.37 µM

Target

A.actinomycetemcomitans

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Weakly active against Gram- A.actinomycetemcomitans (MIC 222.37 uM), E.coli (MIC 114 uM). Its activity against Gram+ bacteria and fungi >200 uM.
Evidence 2 Activity

Activity

MIC
Antibacterial
114 µM

Target

E.coli

Source & Reference

dbAMP

Other

Weakly active against Gram- A.actinomycetemcomitans (MIC 222.37 uM), E.coli (MIC 114 uM). Its activity against Gram+ bacteria and fungi >200 uM.
Evidence 3 Activity

Activity

MIC
Antifungal
222.37 µM

Target

A.actinomycetemcomitans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Weakly active against Gram- A.actinomycetemcomitans (MIC 222.37 uM), E.coli (MIC 114 uM). Its activity against Gram+ bacteria and fungi >200 uM.
Evidence 4 Activity

Activity

MIC
Antifungal
114 µM

Target

E.coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Weakly active against Gram- A.actinomycetemcomitans (MIC 222.37 uM), E.coli (MIC 114 uM). Its activity against Gram+ bacteria and fungi >200 uM.
Evidence 5 Activity

Activity

6% Hemolysis
Toxicity
460 µM
Hemolytic Cytotoxic
6% Hemolysis | 460 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Ocellatin peptides from the skin secretion of the South American frog Leptodactylus labyrinthicus (Leptodactylidae): characterization, antimicrobial activities and membrane interactions. | J Venom Anim Toxins Incl Trop Dis | 2017