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Peptide record

TPDB05191

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB05191
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept AI4AVP APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INVLGILGLLGKALSHL
Physicochemical Analysis
C81H143N21O20
RDCEQMFPTWY
L
1731.15
10.10
2
0
10
+1
-1.55
1.482
206.47
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
1
H
2
I
6
L
1
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 2 L: 6 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C81H143N21O20
1731.15
10.10
+1
-1.55
1.482
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.2578459] Hemolysis: ED50=0.7±0.05 µg/ml. Histamine release: ED50=2.0±0.3 µg/ml against guinea pig erythrocytes.

Target

guinea pig erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J Biol Chem. 1985 Feb 10 260(3):1437-144.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.2578459] Hemolysis: ED50=0.7±0.05 µg/ml. Histamine release: ED50=2.0±0.3 µg/ml against guinea pig erythrocytes.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 1985 Feb 10 260(3):1437-144.
Evidence 3 Hemolysis

Activity

[Ref.2578459] Hemolysis: ED50=0.7±0.05 µg/ml. Histamine release: ED50=2.0±0.3 µg/ml against guinea pig erythrocytes.
Hemolysis

Target

guinea pig erythrocytes

Source & Reference

APD_complete APD_hemolytic
J Biol Chem. 1985 Feb 10 260(3):1437-144.
DRAMP4
APD_complete APD_hemolytic