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Peptide record

TPDB05187

Vibi H Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB05187
Vibi H
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
GLLPCAESCVYIPCLTTVIGCSCKSKVCYKN
Physicochemical Analysis
C142H235N35O42S6
RDQHMFW
C
3297.00
8.01
3
1
11
+2
1.42
0.668
94.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
101.76
14
Residue Composition
number
1
A
0
R
1
N
0
D
6
C
1
E
0
Q
2
G
0
H
2
I
3
L
3
K
0
M
0
F
2
P
3
S
2
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 3 M: 0 F: 0 P: 2 S: 3 T: 2 W: 0 Y: 2 V: 3
Chemical Descriptors
31
C142H235N35O42S6
3297.00
8.01
+2
1.42
0.668
Free
L
Not Available
Free
Anticancer
Alpine violetViola biflora
Evidence Records 2 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Lung Cancer
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
1.6 µM
Cytotoxic
Cytotoxicity: [Ref.18191970] Cytotoxicity: Human lymphoma cell line U-937 GTB (IC50=1.6 µM).

Source & Reference

NA
DRAMP
Phytochemistry. 2008 Feb 69(4):939-952.