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Peptide record

TPDB05181

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB05181
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VDKPDYRPRPRPPNM
Physicochemical Analysis
C80H128N26O22S1
ACEQGHILFSTW
P
1838.12
10.41
4
2
3
+2
7.45
-2.073
19.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
81.06
2
Residue Composition
number
0
A
3
R
1
N
2
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
5
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 5 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C80H128N26O22S1
1838.12
10.41
+2
7.45
-2.073
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50-100 µM

Target

Escherichia coli D22

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other
Evidence 2 Activity

Activity

MIC
Antibacterial
50-100 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of ac
Evidence 3 Activity

Activity

MIC
Antibacterial
50-100 µM

Target

Alcaligenes faecalis

Source & Reference

dbAMP DRAMP

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of activity but higher in terms of con
Evidence 4 Activity

Activity

MIC
Antifungal
50-100 µM

Target

Escherichia coli D22

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other
Evidence 5 Activity

Activity

MIC
Antifungal
50-100 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP Antifungipept

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of ac
Evidence 6 Activity

Activity

MIC
Antifungal
50-100 µM

Target

Alcaligenes faecalis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of activity but higher in terms of con
Evidence 7 Activity

Activity

MIC
Antiparasitic
50-100 µM

Target

Escherichia coli D22

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other
Evidence 8 Activity

Activity

MIC
Antiparasitic
50-100 µM

Target

S. typhimurium

Source & Reference

dbAMP 3.0 DRAMP

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of ac
Evidence 9 Activity

Activity

MIC
Antiparasitic
50-100 µM

Target

Alcaligenes faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of activity but higher in terms of con
Evidence 10 Activity

Activity

MIC
Antiviral
50-100 µM

Target

Escherichia coli D22

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other
Evidence 11 Activity

Activity

MIC
Antiviral
50-100 µM

Target

S. typhimurium

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of ac
Evidence 12 Activity

Activity

MIC
Antiviral
50-100 µM

Target

Alcaligenes faecalis

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Weakly active against E. coli D22 (MIC 50-100 uM), S. typhimurium (MIC 50-100 uM), and A. faecalis (MIC 50-100 uM). It is weaker than other insect defensins in terms of activity but higher in terms of con
Evidence 13 Activity

Activity

50% Cell death
Toxicity
>54.4 µM
Cytotoxic
50% Cell death | >54.4 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010