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Peptide record

TPDB05172

Antibacterial Hemolysis Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB05172
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
MSGIVEAISNAVKSGLDHDWVNMGTSIADVVAKGADFIAGFFS
Physicochemical Analysis
C197H304N50O62S2
RCQPY
A
4429.00
4.12
3
5
22
-3
3.39
0.528
93.02
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
124.18
8
Residue Composition
number
6
A
0
R
2
N
4
D
0
C
1
E
0
Q
5
G
1
H
4
I
1
L
2
K
2
M
3
F
0
P
5
S
1
T
1
W
0
Y
5
V
Amino Acid Distribution
A: 6 R: 0 N: 2 D: 4 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 4 L: 1 K: 2 M: 2 F: 3 P: 0 S: 5 T: 1 W: 1 Y: 0 V: 5
Chemical Descriptors
43
C197H304N50O62S2
4429.00
4.12
-3
3.39
0.528
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
7530±190 µM
Hemolytic Cytotoxic
50% Hemolysis | 7530±190 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
28070±3060 µM
Hemolytic Cytotoxic
50% Hemolysis | 28070±3060 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
4230±1060 µM
Hemolytic Cytotoxic
50% Hemolysis | 4230±1060 | µM | target cell: Guinea pig erythrocytes

Target

Guinea pig erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
4370±600 µM
Hemolytic Cytotoxic
50% Hemolysis | 4370±600 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
3320±120 µM
Hemolytic Cytotoxic
50% Hemolysis | 3320±120 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. | FEMS Microbiol Lett | 2008
Evidence 6 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis