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Peptide record

TPDB05168

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB05168
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SGYLPGKEYVYKYKGKVF
Physicochemical Analysis
C104H152N22O26
ARNDCQHIMTW
KY
2126.48
9.89
4
1
8
+3
1.28
-0.717
53.89
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5960
280.27
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
0
H
0
I
1
L
4
K
0
M
1
F
1
P
1
S
0
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 4 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 4 V: 2
Chemical Descriptors
18
C104H152N22O26
2126.48
9.89
+3
1.28
-0.717
Evidence Records 19 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>120 µM

Target

Staphylococcus aureus ATCC29213M

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 6
Evidence 2 Activity

Activity

MIC
Antibacterial
>120 µM

Target

Staphylococcus epidermidis ATCC12228

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC2785
Evidence 3 Activity

Activity

MIC
Antibacterial
>120 µM

Target

M.luteus BR2

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D3
Evidence 4 Activity

Activity

MIC
Antibacterial
60-120 µM

Target

M. luteus A270

Source & Reference

dbAMP DRAMP

Other

CC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. m
Evidence 5 Activity

Activity

MIC
Antibacterial
60-120 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP DRAMP

Other

ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae b
Evidence 6 Activity

Activity

MIC
Antibacterial
60-120 µM

Target

S. marcescens ATCC4112

Source & Reference

dbAMP DRAMP

Other

uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. g
Evidence 7 Activity

Activity

MIC
Antibacterial
7.5-30 µM

Target

Candida albicans MDM8 or IOC4558

Source & Reference

dbAMP DRAMP

Other

> 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi
Evidence 8 Activity

Activity

MIC
Antibacterial
3.8-7.5 µM

Target

C. guilliermondii

Source & Reference

dbAMP DRAMP

Other

uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi A.niger (MIC> 120 uM), C.herbarum A
Evidence 9 Activity

Activity

MIC
Antibacterial
3.8-7.5 µM

Target

C. tropicalis

Source & Reference

dbAMP DRAMP

Other

fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi A.niger (MIC> 120 uM), C.herbarum ATCC26362 (MIC> 120 uM), and P.farin
Evidence 10 Activity

Activity

MIC
Antifungal
>120 µM

Target

Staphylococcus aureus ATCC29213M

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 6
Evidence 11 Activity

Activity

MIC
Antifungal
>120 µM

Target

Staphylococcus epidermidis ATCC12228

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC2785
Evidence 12 Activity

Activity

MIC
Antifungal
>120 µM

Target

M.luteus BR2

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D3
Evidence 13 Activity

Activity

MIC
Antifungal
60-120 µM

Target

M. luteus A270

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

CC29213M (MIC>120 uM), S. epidermidis ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. m
Evidence 14 Activity

Activity

MIC
Antifungal
60-120 µM

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ATCC12228 (MIC>120 uM), M.luteus BR2 (MIC >120 uM), M. luteus A270 (MIC 60-120 uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae b
Evidence 15 Activity

Activity

MIC
Antifungal
60-120 µM

Target

S. marcescens ATCC4112

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), Gram- P. aeruginosa ATCC27853 (MIC 60-120 uM), E.coli D31 or SBS363 (MIC > 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. g
Evidence 16 Activity

Activity

MIC
Antifungal
7.5-30 µM

Target

Candida albicans MDM8 or IOC4558

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

> 120 uM), S. marcescens ATCC4112 (MIC 60-120 uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi
Evidence 17 Activity

Activity

MIC
Antifungal
3.8-7.5 µM

Target

C. guilliermondii

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), E.cloacae beta12 (MIC > 120 uM), fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi A.niger (MIC> 120 uM), C.herbarum A
Evidence 18 Activity

Activity

MIC
Antifungal
3.8-7.5 µM

Target

C. tropicalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fungi C. albicans MDM8 or IOC4558 (MIC 7.5-30 uM), C. guilliermondii (MIC 3.8-7.5 uM) and C. tropicalis (MIC 3.8-7.5 uM), filamentous fungi A.niger (MIC> 120 uM), C.herbarum ATCC26362 (MIC> 120 uM), and P.farin
Evidence 19 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles. | PLoS One | 2016