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Peptide record

TPDB05142

Antibacterial Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB05142
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FFFLPSLIGGLVSAIK
Physicochemical Analysis
C86H133N17O19
RNDCEQHMTWY
LF
1709.10
10.10
1
0
10
+1
-4.07
1.681
146.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
0
M
3
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 0 F: 3 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C86H133N17O19
1709.10
10.10
+1
-4.07
1.681
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.4-0.8 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 0.4-0.8 uM), S. aureus (MIC 13-25 uM), B. subtilis (MIC 0.8-1.6 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
13-25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 0.4-0.8 uM), S. aureus (MIC 13-25 uM), B. subtilis (MIC 0.8-1.6 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
0.8-1.6 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

Active against E. coli (MIC 0.4-0.8 uM), S. aureus (MIC 13-25 uM), B. subtilis (MIC 0.8-1.6 uM).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>25 µM
Hemolytic Cytotoxic
50% Hemolysis | >25 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Complete de novo sequencing of antimicrobial peptides in the venom of the scorpion Isometrus maculatus. | Toxicon | 2017
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis