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Peptide record

TPDB05137

Antibacterial Antifungal Antiviral Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB05137
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AVPpred-BWR ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
DLWNSIKDMAAAAGRAALNAVTGMVNQ
Physicochemical Analysis
C118H194N36O38S2
CEHFPY
A
2789.18
6.90
2
2
15
-0
1.60
0.159
90.74
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5500
197.19
6
Residue Composition
number
7
A
1
R
3
N
2
D
0
C
0
E
1
Q
2
G
0
H
1
I
2
L
1
K
2
M
0
F
0
P
1
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 1 N: 3 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 2 K: 1 M: 2 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
27
C118H194N36O38S2
2789.18
6.90
-0
1.60
0.159
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
692 µM
Hemolytic Cytotoxic
50% Hemolysis | 692 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Schistosoma mansoni dermaseptin-like peptide: structural and functional characterization. | J Parasitol | 2005
Evidence 2 Activity

Activity

80% Hemolysis
Toxicity
1000 µM
Hemolytic Cytotoxic
80% Hemolysis | 1000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Schistosoma mansoni dermaseptin-like peptide: structural and functional characterization. | J Parasitol | 2005
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:6539015]Show hemolytic activity on human and duck erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
J Parasitol. 2005 Dec 91(6):1340-1351.