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Peptide record

TPDB05134

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB05134
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLGVLGSVAKHVLPHVVPVIAEHL
Physicochemical Analysis
C120H200N32O29
RNDCQMFTWY
V
2555.11
8.06
4
1
14
+0
3.92
1.204
171.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
3
H
1
I
5
L
1
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 3 I: 1 L: 5 K: 1 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 6
Chemical Descriptors
25
C120H200N32O29
2555.11
8.06
+0
3.92
1.204
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
22 µM
Cytotoxic
50% Cell death | 22 | µM | target cell: CD4+ T Lymphocytes

Target

CD4+ T Lymphocytes

Source & Reference

NA
DBAASP
Inhibition of HIV Infection by Caerin 1 Antimicrobial Peptides | Peptides | 2015
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.26026377]CD4+ T Lymphocytes:50% cell death at 22 µM.

Source & Reference

NA
DRAMP
Peptides. 2015 Sep 71:296-303. ##J. Chem. Res. 1993 138: 910-936.