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Peptide record

TPDB05133

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB05133
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSLIPHAINAVSAIAKHN
Physicochemical Analysis
C93H150N26O24
RDCEQGMTWY
A
2016.37
10.10
3
0
11
+1
0.67
0.779
138.95
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
4
A
0
R
2
N
0
D
0
C
0
E
0
Q
0
G
2
H
3
I
2
L
1
K
0
M
1
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 2 I: 3 L: 2 K: 1 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C93H150N26O24
2016.37
10.10
+1
0.67
0.779
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
2 µM
Hemolytic Cytotoxic
0% Hemolysis | 2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus | Peptides | 2005
Evidence 2 Activity

Activity

2% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
2% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus | Peptides | 2005
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:15752569]0.3% hemolytic activity at 4 µM, 0.57% hemolytic activity at 8 µM, 0.6% hemolytic activity at 16 µM, 0.98% hemolytic activity at 32 µM, 1.98% hemolytic activity at 64 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2005 Apr 26(4):565-573.##Peptides. 2008 Oct 29(10):1633-1644.