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Peptide record

TPDB05130

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB05130
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPAIFRMAAKVVPTIICSITKKC
Physicochemical Analysis
C123H208N30O28S3
NDEQGHWY
I
2651.37
10.32
4
0
13
+4
-0.05
1.104
117.92
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.71
5
Residue Composition
number
3
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
4
I
1
L
3
K
1
M
2
F
2
P
1
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 1 K: 3 M: 1 F: 2 P: 2 S: 1 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C123H208N30O28S3
2651.37
10.32
+4
-0.05
1.104
Evidence Records 3 records
Evidence 1 Activity

Activity

LC50
Hemolysis
0.5 µM
[Ref.8163497]LC50=0.5 µM against human erythrocytes

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J Biol Chem. 1994 Apr 22 269(16):11956-11961.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

LC50
Toxicity
0.5 µM
Hemolytic
Hemolytic_activity: [Ref.8163497]LC50=0.5 µM against human erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
Evidence 3 Hemolysis

Activity

0.5 µM
LC50
[Ref.8163497]LC50=0.5 µM against human erythrocytes
Hemolysis

Target

human erythrocytes

Source & Reference

APD_complete APD_hemolytic
J Biol Chem. 1994 Apr 22 269(16):11956-11961.
DRAMP4
APD_complete APD_hemolytic