Back to search

Peptide record

TPDB05128

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05128
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RVCYAIPLPIC
Physicochemical Analysis
C57H94N14O13S2
NDEQGHKMFSTW
CIP
1247.58
8.28
1
0
6
+1
-0.99
1.345
141.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1615
129.45
3
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
11
C57H94N14O13S2
1247.58
8.28
+1
-0.99
1.345
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Staphylococcus aureus ATCC 8530

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevi
Evidence 2 Activity

Activity

MIC
Antibacterial
60 µg/mL

Target

P. putida NCIM 2102

Source & Reference

dbAMP DRAMP

Other

Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

S. cerevisiae ATCC 8530

Source & Reference

dbAMP DRAMP

Other

50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Staphylococcus aureus ATCC 8530

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevi
Evidence 5 Activity

Activity

MIC
Antifungal
60 µg/mL

Target

P. putida NCIM 2102

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

S. cerevisiae ATCC 8530

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Staphylococcus aureus ATCC 8530

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevi
Evidence 8 Activity

Activity

MIC
Antiparasitic
60 µg/mL

Target

P. putida NCIM 2102

Source & Reference

DRAMP

Other

Active against S. aureus ATCC 8530 (MIC 50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

S. cerevisiae ATCC 8530

Source & Reference

DRAMP

Other

50 ug/ml), E. coli W 160.37 (MIC 60 ug/ml), P. putida NCIM 2102 (MIC 60 ug/ml), and yeast S. cerevisiae ATCC 8530 (MIC 100 ug/ml).
Evidence 10 Activity

Activity

0% Hemolysis
Toxicity
<200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | <200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina. | J Biol Chem | 2001
Evidence 11 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 µg/ml against rat erythrocytes.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2001 Jan 26 276(4):2701-2707.