Back to search

Peptide record

TPDB05125

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05125
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ALWKNMLKGIGKLAGQAALGAVKTLVGAES
Physicochemical Analysis
C135H231N37O37S1
RDCHFPY
A
2996.60
10.55
4
1
16
+3
1.23
0.470
117.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
183.54
4
Residue Composition
number
6
A
0
R
1
N
0
D
0
C
1
E
1
Q
5
G
0
H
1
I
5
L
4
K
1
M
0
F
0
P
1
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 5 H: 0 I: 1 L: 5 K: 4 M: 1 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
30
C135H231N37O37S1
2996.60
10.55
+3
1.23
0.470
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
22 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
5.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
1.3 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
2.7 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
22 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
5.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
1.3 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
2.7 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
22 µM

Target

Enterococcus faecalis

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 10 Activity

Activity

MIC
Antiparasitic
5.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
1.3 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
2.7 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. faecalis (MIC 22 uM), P. aeruginosa (MIC 5.4 uM), E. coli (MIC 1.3 uM), S. aureus (MIC 2.7 uM).
Evidence 13 Activity

Activity

100% Hemolysis
Toxicity
>36.0 µM
Hemolytic Cytotoxic
100% Hemolysis | >36.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta. | Peptides | 1999
Evidence 14 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.