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Peptide record

TPDB05123

Tat2 Antibacterial Antifungal Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB05123
Tat2
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CPPsite3.0 MLCPP 2.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RKKRRQRRRRKKRRQRRR
Physicochemical Analysis
C106H210N60O21
ANDCEGHILMFPSTWYV
R
2661.22
13.44
16
0
0
+16
14.84
-4.256
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
12
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 12 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C106H210N60O21
2661.22
13.44
+16
14.84
-4.256
Free
L
Cationic
Dimer
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Microspores (from triticale (Sunray))

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Dimer L Cationic
Synthetic
In vitro
CCSCCCCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Fusarium dimerum and eyes of New Zealand white rabbits

Assay & Model

Female Balb/c mice aged 6 – 8 weeks
Female Balb/c mice aged 6 – 8 weeks

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Dimer L Cationic
Synthetic
FITC and Natamycin
5-fold higher uptake compared to natamycin alone.
In-vitro, in-vivo and ex vivo
Additional Detail Fields 1 fields
CCSCCCCCC