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Peptide record

TPDB05122

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB05122
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GVVDILKGAAKDLAGHLATKVMNKL
Physicochemical Analysis
C114H200N32O32S1
RCEQFPSWY
ALK
2563.10
10.16
5
2
13
+2
4.72
0.408
128.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
1
N
2
D
0
C
0
E
0
Q
3
G
1
H
1
I
4
L
4
K
1
M
0
F
0
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 1 L: 4 K: 4 M: 1 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
25
C114H200N32O32S1
2563.10
10.16
+2
4.72
0.408
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
50% Hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and properties of laticeptin, an antimicrobial peptide from skin secretions of the South American frog Leptodactylus laticeps. | Protein Pept Lett | 2006
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.