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Peptide record

TPDB05121

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB05121
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
YVSCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF
Physicochemical Analysis
C214H319N67O56S6
EQHKMW
R
4918.66
9.54
8
1
14
+7
-2.33
-0.214
34.76
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6335
128.80
17
Residue Composition
number
1
A
8
R
1
N
1
D
6
C
0
E
0
Q
5
G
0
H
1
I
1
L
0
K
0
M
5
F
1
P
5
S
1
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 1 C: 6 E: 0 Q: 0 G: 5 H: 0 I: 1 L: 1 K: 0 M: 0 F: 5 P: 1 S: 5 T: 1 W: 0 Y: 4 V: 2
Chemical Descriptors
42
C214H319N67O56S6
4918.66
9.54
+7
-2.33
-0.214
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0% Hemolysis | 10 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins | J Biol Chem | 1999