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Peptide record

TPDB05113

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB05113
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLGGLLGPLLGGGGGGGGGLL
Physicochemical Analysis
C79H136N22O23
ARNDCEQHIKMFSTWYV
G
1762.08
6.02
0
0
8
-0
-3.90
1.073
141.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
13
G
0
H
0
I
8
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 13 H: 0 I: 0 L: 8 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C79H136N22O23
1762.08
6.02
-0
-3.90
1.073
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 3 Activity

Activity

MIC
Antibacterial
75 µM

Target

Citrobacter freundii

Source & Reference

dbAMP DRAMP

Other

ed the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 4 Activity

Activity

MIC
Antifungal
8 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 5 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 6 Activity

Activity

MIC
Antifungal
75 µM

Target

Citrobacter freundii

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ed the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 7 Activity

Activity

MIC
Antiparasitic
8 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 8 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 9 Activity

Activity

MIC
Antiparasitic
75 µM

Target

Citrobacter freundii

Source & Reference

DRAMP

Other

ed the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 10 Activity

Activity

MIC
Antiviral
8 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 11 Activity

Activity

MIC
Antiviral
50 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

The peptide inhibited the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 12 Activity

Activity

MIC
Antiviral
75 µM

Target

Citrobacter freundii

Source & Reference

DRAMP

Other

ed the growth of Gram-negative bacteria P. aeruginosa (MIC 8 uM), E. coli (MIC 50 uM) and C. freundii (MIC 75 uM). Formatted 8/2024
Evidence 13 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leptoglycin: a new Glycine/Leucine-rich antimicrobial peptide isolated from the skin secretion of the South American frog Leptodactylus pentadactylus (Leptodactylidae). | Toxicon | 2009
Evidence 14 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.19298834]Non-hemolytic activity was observed at 2-200 µM concentration

Target

erythrocytes

Source & Reference

NA
DRAMP
Toxicon. 2009 Jul 54(1):23-32.