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Peptide record

TPDB05108

Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB05108
Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 dbAMP DRAMP Antifungipept AVPpred-BWR APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Anticancer, and other sources) peptide sequence curated from Peptipedia, AntiBP3, dbAMP, and other sources, with an available 3D structural model.
Sequence
IDWLKLGKMVMDVL
Physicochemical Analysis
C77H129N17O19S2
ARNCEQHFPSTY
L
1661.09
6.87
2
2
9
-0
0.29
0.857
152.86
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
331.11
0
Residue Composition
number
0
A
0
R
0
N
2
D
0
C
0
E
0
Q
1
G
0
H
1
I
3
L
2
K
2
M
0
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 2 M: 2 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
14
C77H129N17O19S2
1661.09
6.87
-0
0.29
0.857
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
38 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baum
Evidence 2 Activity

Activity

MIC
Antibacterial
19 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
38 µM

Target

B. cereus

Source & Reference

dbAMP DRAMP

Other

tivity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
310 µM

Target

P.aeruginosa

Source & Reference

dbAMP DRAMP

Other

- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
12.5-25 µM

Target

A. baumannii

Source & Reference

dbAMP DRAMP

Other

38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
38 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baum
Evidence 7 Activity

Activity

MIC
Antifungal
19 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
38 µM

Target

B. cereus

Source & Reference

dbAMP DRAMP Antifungipept

Other

tivity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
310 µM

Target

P.aeruginosa

Source & Reference

dbAMP DRAMP Antifungipept

Other

- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
12.5-25 µM

Target

A. baumannii

Source & Reference

dbAMP DRAMP Antifungipept

Other

38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
38 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baum
Evidence 12 Activity

Activity

MIC
Antiparasitic
19 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 13 Activity

Activity

MIC
Antiparasitic
38 µM

Target

B. cereus

Source & Reference

DRAMP

Other

tivity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 14 Activity

Activity

MIC
Antiparasitic
310 µM

Target

P.aeruginosa

Source & Reference

DRAMP

Other

- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
12.5-25 µM

Target

A. baumannii

Source & Reference

DRAMP

Other

38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 16 Activity

Activity

MIC
Antiviral
38 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baum
Evidence 17 Activity

Activity

MIC
Antiviral
19 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Activity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 18 Activity

Activity

MIC
Antiviral
38 µM

Target

B. cereus

Source & Reference

DRAMP

Other

tivity against G+ and G- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 19 Activity

Activity

MIC
Antiviral
310 µM

Target

P.aeruginosa

Source & Reference

DRAMP

Other

- bacteria such as E. coli (MIC 38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 20 Activity

Activity

MIC
Antiviral
12.5-25 µM

Target

A. baumannii

Source & Reference

DRAMP

Other

38 uM), S. aureus (MIC 19 uM), and B. cereus (MIC 38 uM), P.aeruginosa (MIC 310 uM), and A. baumannii (MIC 12.5-25 uM).
Evidence 21 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Rat polymorphonucleated leukocytes

Target

Rat polymorphonucleated leukocytes

Source & Reference

NA
DBAASP
Characterization of two novel polyfunctional mastoparan peptides from the venom of the social wasp Polybia paulista. | Peptides | 2009
Evidence 22 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.