Back to search

Peptide record

TPDB05078

CyO4 Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05078
CyO4
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GIPCGESCVWIPCISSAIGCSCKNKVCYRN
Physicochemical Analysis
C134H216N38O40S6
DQHLMFT
C
3191.78
8.02
3
1
9
+2
1.60
0.353
74.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
230.75
13
Residue Composition
number
1
A
1
R
2
N
0
D
6
C
1
E
0
Q
3
G
0
H
4
I
0
L
2
K
0
M
0
F
2
P
4
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 4 L: 0 K: 2 M: 0 F: 0 P: 2 S: 4 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
30
C134H216N38O40S6
3191.78
8.02
+2
1.60
0.353
Cyclized
L
Cyclic
Cyclized
Antimicrobial,Cytotoxic
Viola odorata
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 9.8 µM
Anticancer
9.8 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.