Back to search

Peptide record

TPDB05056

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard

14 amino acids

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB05056

Activity

Antibacterial Anticancer Antifungal Antiparasitic Toxicity

Activity_category_statistics

Anti-infective peptides Cancer-related peptides Toxicity and safety peptides

Database_Source

AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0

Sequence_Type

standard

Has_Modification No

Description A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.

Sequence

INLKAIAAMAKKLL

FASTA

>TPDB05056|Antibacterial;Anticancer;Antifungal;Antiparasitic;Toxicity|length=14
INLKAIAAMAKKLL

Formula C69H128N18O16S1

Absent Amino Acids RDCEQGHFPSTWYV

Common Amino Acids A

Mass 1497.95

PI 10.84

Basic Residues 3

Acidic Residues 0

Hydrophobic Residues 10

Net Charge +3

Boman Index 0.18

Hydrophobicity 1.021

Aliphatic Index 167.86

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 1

number

Amino Acid Distribution

A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0

Length

Formula

C69H128N18O16S1

Mass

1497.95

10.84

Net Charge

Boman Index

0.18

Hydrophobicity

1.021

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 3 µg/mL

Target

Target Organism Escherichia coli ATCC25922

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.5 µM

Target

Target Organism Staphylococcus aureus ATCC2592

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 12 µg/mL

Target

Target Organism Candida albicans ATCC2002

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 3 µg/mL

Target

Target Organism Escherichia coli ATCC25922

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.5 µM

Target

Target Organism Staphylococcus aureus ATCC2592

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 12 µg/mL

Target

Target Organism Candida albicans ATCC2002

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 3 µg/mL

Target

Target Organism Escherichia coli ATCC25922

Source & Reference

Database Source DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets.

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1.5 µM

Target

Target Organism Staphylococcus aureus ATCC2592

Source & Reference

Database Source DRAMP

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 12 µg/mL

Target

Target Organism Candida albicans ATCC2002

Source & Reference

Database Source DRAMP

Other

Evidence Text

Active against E. coli ATCC25922 (MIC 3 ug/ml), S. aureus ATCC2592 (MIC 1.5 uM), and C. albicans ATCC2002 (MIC 12 ug/ml).

Evidence 10 Activity

Activity

Activity Endpoint 77% degranulation

Detail Source Activity Toxicity

Activity Measurement 10 µg/mL

Toxicity Type Cytotoxic

Toxicity Raw

77% degranulation | 10 | µg/mL | target cell: Rat mast cells

Target

Target Cell Rat mast cells

Source & Reference

Database Source NA

Source Database DBAASP

Reference

The mastoparanogen from wasp | Peptides | 2006