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Peptide record

TPDB05024

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB05024
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSLIPHAINAVSAIAKHF
Physicochemical Analysis
C98H153N25O23
RDCEQGMTWY
A
2049.45
10.10
3
0
12
+1
-0.88
1.111
138.95
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
2
H
3
I
2
L
1
K
0
M
2
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 2 I: 3 L: 2 K: 1 M: 0 F: 2 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C98H153N25O23
2049.45
10.10
+1
-0.88
1.111
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
0% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation and biochemical characterization of peptides presenting antimicrobial activity from the skin of Phyllomedusa hypochondrialis | Peptides | 2006
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
34.42 µM
Cytotoxic
50% Cytotoxicity | 34.42 | µM | target cell: Murine peritoneal macrophages

Target

Murine peritoneal macrophages

Source & Reference

NA
DBAASP
Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi. | Exp Parasitol | 2013