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Peptide record

TPDB05020

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB05020
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFGWLIKGAIHAGKAIHGLIH
Physicochemical Analysis
C112H168N30O22
RNDCEQMPSTYV
GI
2286.75
10.60
5
0
12
+2
-2.08
0.795
125.71
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
240.52
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
3
H
4
I
2
L
2
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 3 I: 4 L: 2 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C112H168N30O22
2286.75
10.60
+2
-2.08
0.795
Evidence Records 4 records
Evidence 1 Activity

Activity

EC50
Toxicity
20.5 µM
Cytotoxic
EC50 | 20.5 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream. | Biochemistry | 2007
Evidence 2 Activity

Activity

EC50
Toxicity
34.8 µM
Cytotoxic
EC50 | 34.8 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream. | Biochemistry | 2007
Evidence 3 Activity

Activity

EC50
Toxicity
17.3 µM
Cytotoxic
EC50 | 17.3 | µM | target cell: Human fibroblasts MRC-5 SV2

Target

Human fibroblasts MRC-5 SV2

Source & Reference

NA
DBAASP
Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream. | Biochemistry | 2007
Evidence 4 Activity

Activity

EC50
Toxicity
28.1 µM
Cytotoxic
EC50 | 28.1 | µM | target cell: Human fibroblasts MRC-5 SV2

Target

Human fibroblasts MRC-5 SV2

Source & Reference

NA
DBAASP
Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream. | Biochemistry | 2007