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Peptide record

TPDB05004

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB05004
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ATCDLLSGIGVQHSACALHCVFRGNRGGYCTGKGICVCRN
Physicochemical Analysis
C171H279N57O51S6
EMPW
G
4141.81
8.31
6
1
13
+3
2.49
0.283
78.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
45.03
14
Residue Composition
number
3
A
3
R
2
N
1
D
6
C
0
E
1
Q
7
G
2
H
2
I
3
L
1
K
0
M
1
F
0
P
2
S
2
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 3 N: 2 D: 1 C: 6 E: 0 Q: 1 G: 7 H: 2 I: 2 L: 3 K: 1 M: 0 F: 1 P: 0 S: 2 T: 2 W: 0 Y: 1 V: 3
Chemical Descriptors
40
C171H279N57O51S6
4141.81
8.31
+3
2.49
0.283
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Activity against B. megaterium IAM 1166, B. circulans IFO 3967, C. glutamicum ATCC1 3059(IC50 Updated 4/2019
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Activity against B. megaterium IAM 1166, B. circulans IFO 3967, C. glutamicum ATCC1 3059(IC50 Updated 4/2019
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Activity against B. megaterium IAM 1166, B. circulans IFO 3967, C. glutamicum ATCC1 3059(IC50 Updated 4/2019
Evidence 4 Activity

Activity

1% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
1% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010